Deep Six

Deep Six may refer to:

• Deep Six (album), a 1986 compilation album
• Deep Six (novel), a Dirk Pitt adventure novel by Clive Cussler
• Deep Six (Alberta politics), a group of fiscally conservative members of the Legislative Assembly of Alberta, Canada
• Deep Six (Marvel Comics), two Marvel Comics teams with the same name
• Deep Six (DC Comics), a DC Comics supervillain team
• Deep Six (G.I. Joe), a fictional character in the G.I. Joe universe
• The Deep Six, a World War II war film starring Alan Ladd
• Deep Six, a fictional novel by Timothy McGee, a character in the NCIS universe
• "Deep Six", an episode of Teen Titans
• "The Deep Six", a Randy Striker adventure thriller by Randy Wayne White
• "Deep Six", a song that appeared on the 1997 album Underdogs, by Matthew Good